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clavulanate biosynthesis
| State Icon | Reaction | EC-Number | Confidence maximal confidence score from EnzymeDetector | |
|---|---|---|---|---|
| clavaminate <=> Clavulanate-9-aldehyde |
not assigned |
–
|
||
| deoxyamidinoproclavaminate + 2-oxoglutarate + O2 <=> amidinoproclavaminate + succinate + CO2 |
1.14.11.21
clavaminate synthase
|
–
|
||
| N2-(2-carboxyethyl)-L-arginine + ATP <=> deoxyamidinoproclavaminate + AMP + diphosphate |
6.3.3.4
(carboxyethyl)arginine beta-lactam-synthase
|
–
|
||
| amidinoproclavaminate + H2O <=> proclavaminate + Urea |
3.5.3.22
proclavaminate amidinohydrolase
|
–
|
||
| proclavaminate + 2-oxoglutarate + O2 <=> dihydroclavaminate + CO2 + H2O + succinate |
1.14.11.21
clavaminate synthase
|
–
|
||
| dihydroclavaminate + 2-oxoglutarate + O2 <=> clavaminate + CO2 + H2O + succinate |
1.14.11.21
clavaminate synthase
|
–
|
||
| D-glyceraldehyde_3-phosphate + L-arginine <=> N2-(2-carboxyethyl)-L-arginine + phosphate + H+ |
2.5.1.66
N2-(2-carboxyethyl)arginine synthase
|
–
|
||
| H+ + Clavulanate-9-aldehyde + NADPH <=> clavulanic_acid + NADP+ |
not assigned |
–
|
||